NPR

He Started Puberty When He Was 2 Years Old. Now, He's Sharing His Experience

Here & Now's Jeremy Hobson talks with Patrick Burleigh, who due to a rare genetic mutation went through what doctors call "precocious puberty," or testotoxicosis.
Patrick Burleigh (center middle), pictured at age 6, stands with members of his Little League baseball team. (Courtesy of Patrick Burleigh)

One thing all humans have in common is that at a certain point in our childhood, we go through puberty: we get bigger, our bodies change, we often get a little rambunctious and moody, and we mature sexually.

But imagine if those changes occurred not when you were 11 or 13 or 15 years old, but when you were a toddler. That was the experience of Patrick Burleigh, who has a rare genetic mutation that triggers testosterone production far younger than normal.

Doctors call it precocious puberty.

“It’s extremely rare — it’s estimated that there might be like fewer than 1,000 of us,” says Burleigh, who  in New York magazine. “And basically it’s a mutation of the luteinizing hormone chorionic gonadotropin receptor gene, which is responsible for triggering testosterone production in the testicles.”

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